Diabetes Insipidus

Diabetes Insipidus

Diabetes Insipidus - Kidney Disorders - Nephrogenic Diabetes Insipidus - What is Diabetes Insipidus | Tips on - Find TipsUnlike Diabetes Mellitus, Diabetes Insipidus is a comparatively rare medical condition where the patient suffers from frequent urination, excessive thirst resulting in increased intake of fluid. Symptoms of this are quite similar to that of diabetes mellitus though there is no increased level of blood glucose. Blurred vision is also rarely found. Since this disease is caused by the deficiency of vasopressin, the Antidiuretic hormone (ADH), there is an increased frequency of urination (polyuria), nocturia (waking up frequently at night to urinate) or enuresis (urinating involuntarily in the bed). As a result of this the urine is pale, colorless or watery in appearance instead of being yellow colored. In children, there can be fever, vomiting or diarrhea as a result of this. Diabetes insipidus has the following forms:

Neurogenic diabetes insipidus:

Also known as Central Diabetes Insipidus, this is the most commonly occurring as well as the most dangerous form of Diabetes Insipidus. It results as a result of a lack of vasopressin, the hormone which acts upon the kidney to reduce the urine output. It happens if the pituitary gland is damaged by different diseases or head injury or genetic disorders.

Nephrogenic diabetes insipidus:

This occurs when the kidney fails to respond normally to the antidiuretic hormone (ADH). This is not present from birth and is an acquired condition. This can result from a number of causes, from kidney disorders or systemic disorders to the side-effects of different drugs.

Dipsogenic diabetes insipidus:

This is caused by faulty or damage to the thirst mechanism located in the hypothalamus. As a result there is an increased level of thirst and consequently, fluid-intake. This suppresses the ADH secretion there is increase in urination.

Gestational diabetes insipidus:

This occurs only during pregnancy. This is caused by extreme forms of production of vasopressinase in the placenta, which breaks down ADH.
Each of the forms has different causes and should be treated differently.

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